BRUNTON, VALERIE G.: search on Z-Library

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1

Alkyne-tagged PLGA allows direct visualisation of nanoparticles in vitro and ex vivo by stimulated Raman scattering microscopy

Vanden-Hehir, Sally, Cairns, Stefan A., Lee, Martin, Zoupi, Lida, Shaver, Michael Patrick, Brunton, Valerie G., Williams, Anna, Hulme, Alison Nicola

Journal:

Biomacromolecules

Year:

2019

Language:

english

File:

PDF, 560 KB

english, 2019

2

Mouse models of metastasis: progress and prospects

Gómez-Cuadrado, Laura, Tracey, Natasha, Ma, Ruoyu, Qian, Binzhi, Brunton, Valerie G.

Journal:

Disease Models & Mechanisms

Year:

2017

Language:

english

File:

PDF, 1.04 MB

english, 2017

3

Kindlin-1 protects cells from oxidative damage through activation of ERK signalling

Emmert, Hila, Patel, Hitesh, Brunton, Valerie G.

Journal:

Free Radical Biology and Medicine

Year:

2017

Language:

english

File:

PDF, 876 KB

english, 2017

4

Src and focal adhesion kinase as therapeutic targets in cancer

Valerie G Brunton, Margaret C Frame

Journal:

Current Opinion in Pharmacology

Year:

2008

Language:

english

File:

PDF, 433 KB

english, 2008

5

Src/FAK-mediated regulation of E-cadherin as a mechanism for controlling collective cell movement

Serrels, Alan, Canel, Marta, Brunton, Valerie G., Frame, Margaret C.

Journal:

Cell Adhesion & Migration

Year:

2011

Language:

english

File:

PDF, 967 KB

english, 2011

6

Rapid Discovery and Structure-Activity Relationships of Pyrazolopyrimidines that Potently Suppress Breast Cancer Cell Growth via SRC Kinase Inhibition with Exceptional Selectivity over ABL Kinase

Fraser, Craig, Dawson, John C., Dowling, Reece, Houston, Douglas R., Weiss, Jason T., Munro, Alison F., Muir, Morwenna, Harrington, Lea, Webster, Scott P, Frame, Margaret C, Brunton, Valerie G., Patto

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.59 MB

english, 2016

7

Src-dependent phosphorylation of Scar1 promotes its association with the Arp2/3 complex

Hazel Ardern, Emma Sandilands, Laura M. Machesky, Paul Timpson, Margaret C. Frame, Valerie G. Brunton

Journal:

Year:

2006

Language:

english

File:

PDF, 872 KB

english, 2006

8

A role for epidermal growth factor receptor, c-Src and focal adhesion kinase in an in vitro model for the progression of colon cancer

Brunton, Valerie G, Ozanne, Bradford W, Paraskeva, Christos, Frame, Magaret C

Journal:

Year:

1997

Language:

english

File:

PDF, 666 KB

english, 1997

9

The Protrusive Phase and Full Development of Integrin-Dependent Adhesions in Colon Epithelial Cells Require FAK- and ERKMediated Actin Spike Formation: Deregulation in Cancer Cells

Brunton, Valerie G., Fincham, Valerie J., McLean, Gordon W., Winder, Steven J., Paraskeva, Christos, Marshall, John F., Frame, Margaret C.

Journal:

Year:

2001

Language:

english

File:

PDF, 422 KB

english, 2001

10

Exploring mechanisms of acquired resistance to HER2 (human epidermal growth factor receptor 2)-targeted therapies in breast cancer

Creedon, Helen, Byron, Adam, Main, Joanna, Hayward, Larry, Klinowska, Teresa, Brunton, Valerie G.

Journal:

Biochemical Society Transactions

Year:

2014

Language:

english

File:

PDF, 379 KB

english, 2014

11

Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells

Agochiya, Mahima, Brunton, Valerie G, Owens, Dewi W, Parkinson, E Kenneth, Paraskeva, Christos, Keith, W Nicol, Frame, Margaret C

Journal:

Year:

1999

Language:

english

File:

PDF, 883 KB

english, 1999

12

The role of focal adhesion kinase catalytic activity on the proliferation and migration of squamous cell carcinoma cells

Alan Serrels, Kenneth McLeod, Marta Canel, Andrew Kinnaird, Kathryn Graham, Margaret C Frame, Valerie G Brunton

Journal:

International Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 1.07 MB

english, 2012

13

Cell-signaling targets for antitumour drug development

Valerie G. Brunton, Paul Workman

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1993

Language:

english

File:

PDF, 2.60 MB

english, 1993

14

Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling

Sandilands, Emma, Serrels, Bryan, McEwan, David G., Morton, Jennifer P., Macagno, Juan Pablo, McLeod, Kenneth, Stevens, Craig, Brunton, Valerie G., Langdon, Wallace Y., Vidal, Marcos, Sansom, Owen J.,

Journal:

Nature Cell Biology

Year:

2011

Language:

english

File:

PDF, 4.24 MB

english, 2011

15

The role of focal-adhesion kinase in cancer — a new therapeutic opportunity

McLean, Gordon W., Carragher, Neil O., Avizienyte, Egle, Evans, Jeff, Brunton, Valerie G., Frame, Margaret C.

Journal:

Nature Reviews Cancer

Year:

2005

Language:

english

File:

PDF, 494 KB

english, 2005

16

Inhibition of phospholipid signalling and proliferation of Swiss 3T3 cells by the wortmannin analogue demethoxyviridin

Michael J Cross, Matthew N Hodgkin, Jane A Plumb, Valerie G Brunton, Allison Stewart, Graeme MacAully, Robert Hill, David J Kerr, Paul Workman, Michael J.O Wakelam

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

1997

Language:

english

File:

PDF, 258 KB

english, 1997

17

Use of photoactivation and photobleaching to monitor the dynamic regulation of E-cadherin at the plasma membrane

Canel, Marta, Serrels, Alan, Anderson, Kurt I., Frame, Margaret C., Brunton, Valerie G.

Journal:

Cell Adhesion & Migration

Year:

2010

Language:

english

File:

PDF, 3.16 MB

english, 2010

18

Kindlin1 regulates microtubule function to ensure normal mitosis

Patel, Hitesh, Stavrou, Ifigeneia, Shrestha, Roshan L., Draviam, Viji, Frame, Margaret C., Brunton, Valerie G.

Journal:

Journal of Molecular Cell Biology

Year:

2016

Language:

english

File:

PDF, 1.79 MB

english, 2016

19

N-alkynyl derivatives of 5-fluorouracil: susceptibility to palladium-mediated dealkylation and toxigenicity in cancer cell culture

Weiss, Jason T., Fraser, Craig, Rubio-Ruiz, BelÃ©n, Myers, Samuel H., Crispin, Richard, Dawson, John C., Brunton, Valerie G., Patton, E. Elizabeth, Carragher, Neil O., Unciti-Broceta, Asier

Journal:

Frontiers in Chemistry

Year:

2014

Language:

english

File:

PDF, 2.88 MB

english, 2014

20

Inhibition of cyclin-dependent kinase activity exacerbates H 2 0 2 -induced DNA damage in Kindler syndrome keratinocytes

Emmert, Hila, Culley, Jayne, Brunton, Valerie G

Journal:

Experimental Dermatology

Year:

2019

Language:

english

File:

PDF, 216 KB

english, 2019

21

The fibrotic and immune microenvironments as targetable drivers of metastasis

Boulter, Luke, Bullock, Esme, Mabruk, Zeanap, Brunton, Valerie G.

Journal:

British Journal of Cancer

Year:

2020

File:

PDF, 1.66 MB

2020

22

Investigation of cellular uptake mechanism of functionalised gold nanoparticles into breast cancer using SERS

Kapara, Anastasia, Brunton, Valerie, Graham, Duncan, Faulds, Karen

Journal:

Chemical Science

Year:

2020

File:

PDF, 646 KB

2020

23

LKB1 Haploinsufficiency Cooperates With Kras to Promote Pancreatic Cancer Through Suppression of p21-Dependent Growth Arrest

Jennifer P. Morton, Nigel B. Jamieson, Saadia A. Karim, Dimitris Athineos, Rachel A. Ridgway, Colin Nixon, Colin J. McKay, Ross Carter, Valerie G. Brunton, Margaret C. Frame, Alan Ashworth, Karin A. O

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 3.96 MB

english, 2010

24

Novel roles of PRK1 and PRK2 in cilia and cancer biology

Patel, Hitesh, Li, Jun, Herrero, Ana, Kroboth, Jakob, Byron, Adam, Kriegsheim, Alex Von, Brunton, Valerie, Carragher, Neil, Hurd, Toby, Frame, Margaret

Journal:

Scientific Reports

Year:

2020

File:

PDF, 3.27 MB

2020

25

Characterisation of estrogen receptor alpha (ERÎ±) expression in breast cancer cells and effect of drug treatment using targeted nanoparticles and SERS

Kapara, Anastasia, Brunton, Valerie G., Graham, Duncan, Faulds, Karen

Journal:

The Analyst (Royal Society of Chemistry)

Year:

2020

File:

PDF, 778 KB

2020

26

Focal adhesion kinase is not required for Src-induced formation of invadopodia in KM12C colon cancer cells and can interfere with their assembly

Sebastien Vitale, Egle Avizienyte, Valerie G. Brunton, Margaret C. Frame

Journal:

European Journal of Cell Biology

Year:

2008

Language:

english

File:

PDF, 844 KB

english, 2008

27

QD-filled micelles which combine SPECT and optical imaging with light-induced activation of a platinum(iv) prodrug for anticancer applications

Maldonado, Carmen R., Gómez-Blanco, Nina, Jauregui-Osoro, Maite, Brunton, Valerie G., Yate, Luis, Mareque-Rivas, Juan C.

Journal:

Chemical Communications

Year:

2013

Language:

english

File:

PDF, 1.35 MB

english, 2013

28

Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling

Avizienyte, Egle, Wyke, Anne W., Jones, Robert J., McLean, Gordon W., Westhoff, M. Andrew, Brunton, Valerie G., Frame, Margaret C.

Journal:

Nature Cell Biology

Year:

2002

Language:

english

File:

PDF, 2.79 MB

english, 2002

29

WT1 expression in breast cancer disrupts the epithelial/mesenchymal balance of tumour cells and correlates with the metabolic response to docetaxel

Artibani, Mara, Sims, Andrew H., Slight, Joan, Aitken, Stuart, Thornburn, Anna, Muir, Morwenna, Brunton, Valerie G., Del-Pozo, Jorge, Morrison, Linda R., Katz, Elad, Hastie, Nicholas D., Hohenstein, P

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 2.21 MB

english, 2017

30

Selective tyrosine kinase inhibition of insulin-like growth factor-1 receptor inhibits human and mouse breast cancer-induced bone cell activity, bone remodeling, and osteolysis

Logan, John G, Sophocleous, Antonia, Marino, Silvia, Muir, Morwenna, Brunton, Valerie G, Idris, Aymen I

Journal:

Journal of Bone and Mineral Research

Year:

2013

Language:

english

File:

PDF, 1.62 MB

english, 2013

31

Combining imaging and pathway profiling: an alternative approach to cancer drug discovery

Neil O. Carragher, Valerie G. Brunton, Margaret C. Frame

Journal:

Drug Discovery Today

Year:

2012

Language:

english

File:

PDF, 1.66 MB

english, 2012

32

A Complex between FAK, RACK1, and PDE4D5 Controls Spreading Initiation and Cancer Cell Polarity

Bryan Serrels, Emma Sandilands, Alan Serrels, George Baillie, Miles D. Houslay, Valerie G. Brunton, Marta Canel, Laura M. Machesky, Kurt I. Anderson, Margaret C. Frame

Journal:

Current Biology

Year:

2010

Language:

english

File:

PDF, 983 KB

english, 2010

33

RhoB and Actin Polymerization Coordinate Src Activation with Endosome-Mediated Delivery to the Membrane

Emma Sandilands, Christophe Cans, Valerie J. Fincham, Valerie G. Brunton, Harry Mellor, George C. Prendergast, Jim C. Norman, Giulio Superti-Furga, Margaret C. Frame

Journal:

Developmental Cell

Year:

2004

Language:

english

File:

PDF, 985 KB

english, 2004

34

AXL Inhibitors in Cancer: A Medicinal Chemistry Perspective

Myers, Samuel H., Brunton, Valerie G., Unciti-Broceta, Asier

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.09 MB

english, 2015

35

Raman Imaging of Nanocarriers for Drug Delivery

Vanden-Hehir, Sally, Tipping, William, Lee, Martin, Brunton, Valerie, Williams, Anna, Hulme, Alison

Journal:

Year:

2019

Language:

english

File:

PDF, 3.43 MB

english, 2019

36

The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype

Hari, Priya, Millar, Fraser R., Tarrats, Nuria, Birch, Jodie, Quintanilla, Andrea, Rink, Curtis J., Fernández-Duran, Irene, Muir, Morwenna, Finch, Andrew J., Brunton, Valerie G., Passos, João F., Mort

Journal:

Science Advances

Year:

2019

Language:

english

File:

PDF, 21.64 MB

english, 2019

37

The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype

Hari, Priya, Millar, Fraser R., Tarrats, Nuria, Birch, Jodie, Quintanilla, Andrea, Rink, Curtis J., Fernández-Duran, Irene, Muir, Morwenna, Finch, Andrew J., Brunton, Valerie G., Passos, João F., Mort

Journal:

Science Advances

Year:

2019

File:

PDF, 21.64 MB

2019

38

HO-1 drives autophagy as a mechanism of resistance against HER2-targeted therapies

Tracey, Natasha, Creedon, Helen, Kemp, Alain J., Culley, Jayne, Muir, Morwenna, Klinowska, Teresa, Brunton, Valerie G.

Journal:

Breast Cancer Research and Treatment

Year:

2019

File:

PDF, 2.07 MB

2019

39

Is Expression or Activation of Src Kinase Associated with Cancer-Specific Survival in ER-, PR- and HER2-Negative Breast Cancer Patients?

Beatrix Elsberger, Bingchao A. Tan, Thomas J. Mitchell, Sylvia B.F. Brown, Elizabeth A. Mallon, Sian M. Tovey, Timothy G. Cooke, Valerie G. Brunton, Joanne Edwards

Journal:

The American Journal of Pathology

Year:

2009

Language:

english

File:

PDF, 1.23 MB

english, 2009

40

In vivo imaging of the tumor and its associated microenvironment using combined CARS / 2-photon microscopy

Lee, Martin, Downes, Andy, Chau, You-Ying, Serrels, Bryan, Hastie, Nick, Elfick, Alistair, Brunton, Valerie, Frame, Margaret, Serrels, Alan

Journal:

Year:

2015

Language:

english

File:

PDF, 1.10 MB

english, 2015

41

Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity

Paul Timpson, Gareth E. Jones, Margaret C. Frame, Valerie G. Brunton

Journal:

Current Biology

Year:

2001

Language:

english

File:

PDF, 486 KB

english, 2001

42

The role and therapeutic potential of the autotaxin–lysophosphatidate signalling axis in breast cancer

Teo, Katy, Brunton, Valerie G.

Journal:

Biochemical Journal

Year:

2014

Language:

english

File:

PDF, 609 KB

english, 2014

43

Geldanamycin-induced cytotoxicity in human colon-cancer cell lines: evidence against the involvement of c-Src or DT-diaphorase

Valerie G. Brunton, Gregor Steele, Alexander D. Lewis, P. Workman

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1998

Language:

english

File:

PDF, 456 KB

english, 1998

44

Kindlin-1 regulates mitotic spindle formation by interacting with integrins and Plk-1

Patel, Hitesh, Zich, Judith, Serrels, Bryan, Rickman, Colin, Hardwick, Kevin G., Frame, Margaret C., Brunton, Valerie G.

Journal:

Nature Communications

Year:

2013

Language:

english

File:

PDF, 2.18 MB

english, 2013

45

HER2 overcomes PTEN (loss)-induced senescence to cause aggressive prostate cancer

Imran Ahmad, Rachana Patel, Lukram Babloo Singh, Colin Nixon, Morag Seywright, Robert J. Barnetson, Valerie G. Brunton, William J. Muller, Joanne Edwards, Owen J. Sansom and Hing Y. Leung

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.60 MB

english, 2011

46

ADF and Cofilin1 Control Actin Stress Fibers, Nuclear Integrity, and Cell Survival

Kanellos, Georgios, Zhou, Jing, Patel, Hitesh, Ridgway, Rachel A., Huels, David, Gurniak, Christine B., Sandilands, Emma, Carragher, Neil O., Sansom, Owen J., Witke, Walter, Brunton, Valerie G., Frame

Journal:

Year:

2015

Language:

english

File:

PDF, 6.55 MB

english, 2015

47

Diversity of Matriptase Expression Level and Function in Breast Cancer

Welman, Arkadiusz, Sproul, Duncan, Mullen, Peter, Muir, Morwenna, Kinnaird, Andrew R., Harrison, David J., Faratian, Dana, Brunton, Valerie G., Frame, Margaret C., Li, Jun

Journal:

Year:

2012

Language:

english

File:

PDF, 3.39 MB

english, 2012

48

Spermine toxicity and glutathione depletion in BHK-21/C13 cells

Valerie G. Brunton, M.Helen Grant, Heather M. Wallace

Journal:

Biochemical Pharmacology

Year:

1990

Language:

english

File:

PDF, 926 KB

english, 1990

49

Toxicity of spermine in BHK-21/C13 cells

BRUNTON, VALERIE G., GRANT, M. HELEN, WALLACE, HEATHER M.

Journal:

Biochemical Society Transactions

Year:

1989

Language:

english

File:

PDF, 307 KB

english, 1989

50

Utilizing stimulated Raman scattering microscopy to study intracellular distribution of label-free ponatinib in live cells

Sepp, Kristel, Lee, Martin, Bluntzer, Marie, Helgason, Vignir, Hulme, Alison Nicola, Brunton, Valerie G.

Journal:

Journal of Medicinal Chemistry

Year:

2019

File:

PDF, 619 KB

2019

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